|本期目录/Table of Contents|

[1]陈桂芳,贾丽丹,肖 伟,等.儿童原发性干燥综合征二例报道[J].遵义医科大学学报,2022,(02):242-246.
 Chen Guifang,Jia Lidan,Xiao Wei,et al.Two cases of primary sjogren’s syndrome in children[J].Journal of Zunyi Medical University,2022,(02):242-246.
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儿童原发性干燥综合征二例报道()
     
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《遵义医科大学学报》[ISSN:1000-9035/CN:22-1262/O4]

卷:
期数:
2022年02期
页码:
242-246
栏目:
病例报告
出版日期:
2022-04-25

文章信息/Info

Title:
Two cases of primary sjogren’s syndrome in children
文章编号:
2096-8159(2022)02-0242-05
作者:
陈桂芳1贾丽丹1肖 伟2张 力1
(1.贵州医科大学附属医院 儿科,贵州 贵阳 550004; 2.贵州金域医学检验中心,贵州 贵阳 550001)
Author(s):
Chen Guifang1Jia Lidan1Xiao Wei2Zhang Li1
(1.Department of Pediatrics,Affiliated Hospital of Guizhou Medical University,Guiyang Guizhou 550004,China; 2.Guiyang Guizhuo Jinyu Medical Laboratory Center,Guiyang Guizhou 550001,China)
关键词:
干燥综合征 儿童 甲状腺功能亢进 血小板减少
Keywords:
Sjogren’ s syndrome children Hyperthyroidism thrombocytopenia
分类号:
R725.9
DOI:
-
文献标志码:
B
摘要:
目的 探讨儿童原发性干燥综合征(Primary sjogren’s syndrome,pSS)的临床表现及诊治方法。方法 对2021年8~9月贵州医科大学附属医院儿童肾脏风湿科收治的以甲状腺功能亢进及血小板减少为主要表现,最终确诊为pSS的 2 例患儿临床诊断过程进行回顾性分析,并进行相关文献复习。结果 对患儿进行相关免疫学检查、唇腺病理活检、泪腺功能和唾液腺放射性核素扫描等特殊检查进行诊断,予激素、免疫抑制剂治疗症状体征明显缓解。结论 儿童pSS少见,临床症状多不典型,发病隐匿,早期常以其他系统表现就诊,极易误漏诊。了解pSS 患儿的发病特点并行适当的检查,对早期诊断、早期治疗、改善预后非常重要。
Abstract:
Objective To investigate the clinical manifestations,diagnosis and treatment of primary Sjogren syndrome(pSS)in children,and to provide reference for future clinical diagnosis and treatment.Methods A retrospective analysis was conducted on the clinical diagnosis of 2 cases of pSS with hyperthyroidism and thrombocytopenia as the main manifestations admitted to the Department of Pediatric Renal rheumatology,Affiliated Hospital of Guizhou Medical University from August to September 2021.And the relevant literature is reviewed.Results The cases were diagnosed by immunological examination,labial gland pathological biopsy,lacrimal gland function and salivary gland radionuclide scan,as well as other special examinations.Moreover,the symptoms and signs were significantly relieved by hormone and immunosuppressive therapy.Conclusion pSS is rare in children with atypical clinical symptoms.The onset of occult,early often with other system manifestations,is easy to miss diagnosis.Understanding the characteristics of pSS and appropriate examination are very important for early diagnosis,early treatment and improvement of prognosis.

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备注/Memo

备注/Memo:
[通信作者]张力,男,硕士,副主任医师,研究方向:小儿肾脏风湿性疾病,E-mail:1299219279@qq.com。
更新日期/Last Update: 1900-01-01